Evidence
What the research shows
In clinical studies, tesamorelin has demonstrated a significant 15-20% reduction in visceral fat over a 26-week period at a dosage of 2 mg/day. This GHRH analog also leads to an impressive increase in IGF-1 levels, averaging +81%. Its mechanism involves the activation of GHRH receptors, which stimulates downstream hormonal pathways crucial for metabolic health. While primarily studied in non-human models, the pharmacokinetic profiles indicate promising applications in endocrine research.