Evidence
What the research shows
Sermorelin effectively stimulates growth hormone release, mimicking the action of natural growth hormone-releasing hormone (GHRH). In studies, it has been shown to significantly enhance growth hormone levels and increase insulin-like growth factor 1 (IGF-1), a key mediator of growth hormone effects. While most research has been conducted in animal models, it provides a robust framework for understanding its potential in human applications. Notably, the FDA-approved GHRH analog, Tesamorelin, has demonstrated a 15-20% reduction in visceral fat, indicating the efficacy of GHRH analogs in metabolic health.